Biochem/physiol Actions

Primary TargetSIRT3

Reversible: yes

Secondary Targetp300 HAT

Cell permeable: yes

General description

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).Please note that the molecular weight for this compound is batch-specific due to variable water content.

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Baur, J.A., et al. 2012. Nat. Rev. Drug Discov.11, 443.Minor, R.K., et al. 2011. Sci. Rep.1, 70.r>Huber, J.L., et al. 2010. Future Med. Chem.2, 1751.Pacholec, M., et al. 2010. J. Biol. Chem.285, 8340.Jin, L., et al. 2009. Protein Sci.18, 514.Feige, J.N., et al. 2008. Cell Metab.8, 347.Milne, J.C., et al. 2007. Nature450, 712.

Packaging

Packaged under inert gas

10 mg in Glass bottle

Physical form

A 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Warning

Toxicity: Standard Handling (A)